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U-47700 is an opioid analgesic drug developed by a team at Upjohn, which acts as a selective agonist of the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has approximately 7.5 times the potency of morphine in animal models. Also, order u47700 online now.

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U-47700 is a structural isomer of the earlier opioid AH-7921 and is the result of a large body of work elucidating the quantitative structure-activity relationship of the scaffold. Upjohn searched for key moieties that yielded the greatest activity and filed over a dozen patents on related compounds, each optimizing a moiety until they found U-47700 to be the most active.

U-47700 has become the primary compound of kappa-opioid receptor selective ligands such as U-50488, U-51754 (containing a single methylene spacer difference), and U-69,593, which share very similar structures. Although not used medically, kappa-selective ligands are used in research. Buy U-47700 online

Uses of U47700

U47700, like other opioids, produces a number of unwanted side effects that are commonly known as “crashes.” These include agitation, irritability, negative emotional states, cognitive fatigue, difficulty thinking, anxiety, depression, and lack of motivation.

U47700 has a marked dose-dependent toxicity due to its extreme potency compared to traditional opioids and opiates. This makes it less than ideal recreational compound with a significant risk of harm to the user. Therefore, caution should be exercised regarding the dose. So you can order the powder online and have it delivered without any problems. U-47700 for sale.